Features of scaffolds and their manufacturing technology for using the regenerative surgery 

Konstantin I. Sergatskiy, Doctor of medical sciences, associate professor, professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia); coloproctologist of the department of coloproctology, Penza Regional Clinical Hospital named after N. N. Burdenko (28 Lermontova street, Penza, Russia), E-mail: sergatsky@bk.ru
Valeriy I. Nikol'skiy, Doctor of medical sciences, professor, professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: pmisurg@gmail.com
Daniil P. Sheremet, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: sheremet.danya1@yandex.ru
Mukhamed Al’dzhabr, Assistant of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: pmisurg@gmail.com 
Dmitriy V. Mizonov, Coloproctologist, Health center № 4 of the Administration of the President of the Russian Federation (Moscow, Russia), E-mail: pmisurg@gmail.com
Aleksandr V. Shabrov, Candidate of medical sciences, associate professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia); surgeon, Penza Regional Clinical Hospital named after N. N. Burdenko (28 Lermontova street, Penza, Russia), E-mail: alexundead12@yandex.ru 

Background. The rapid development and improvement of methods for replenishing lost defects in human tissues based on the use of scaffold technology in regenerative medicine and surgery, in particular, convincingly proves the relevance and prospects of this industry. Materials and methods. High-tech processes of modern scaffold matrices production suggest replacing obsolete treatment methods in restorative medicine with new developments shortly. At the same time, additional studies are needed on the possibility of applying and evaluating the results of the implementation of the applied methods. Results and conclusions. The fundamental goal of the development of this area is the development and application of universal materials that will be used in various branches of restorative medicine when replacing defects in human tissues and organs. 

scaffold technologies, regenerative surgery, regenerative medicine, transplantation, tissue engineering 

Sergatskiy K.I., Nikol'skiy V.I., Sheremet D.P., Al'dzhabr M., Mizonov D.V., Shabrov A.V. Features of scaffolds and their manufacturing technology for using the regenerative surgery. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2022;(3):124–133. (In Russ.). doi:10.21685/2072-3032-2022-3-11